Erratum to: FoundationOne CDx testing accurately determines whole arm 1p19q codeletion status in gliomas
نویسندگان
چکیده
منابع مشابه
IDH mutation, 1p19q codeletion and ATRX loss in WHO grade II gliomas
BACKGROUND Epigenetic, genetic, and molecular studies have identified several diagnostic and prognostic markers in diffuse gliomas. Their importance for evaluating WHO grade II gliomas has yet to be specifically delineated. METHODS We analyzed markers, including IDH mutation(IDHmut), 1p19q codeletion(1p19qcodel), ATRX expression loss(ATRX loss) and p53 overexpression, and outcomes in 159 pati...
متن کاملGenetic markers predictive of chemosensitivity and outcome in gliomatosis cerebri.
BACKGROUND Up-front temozolomide (TMZ) has been recently proposed as a treatment for gliomatosis cerebri (GC), but no predictive or prognostic markers have been identified so far. Because 1p19q codeletion and methylguanine methyl transferase promoter (MGMTP) methylation have been correlated with chemosensitivity of gliomas, their value was investigated in a cohort of patients with GC treated wi...
متن کاملIDH Mutations: Genotype-Phenotype Correlation and Prognostic Impact
IDH1/2 mutation is the most frequent genomic alteration found in gliomas, affecting 40% of these tumors and is one of the earliest alterations occurring in gliomagenesis. We investigated a series of 1305 gliomas and showed that IDH mutation is almost constant in 1p19q codeleted tumors. We found that the distribution of IDH1(R132H) , IDH1(nonR132H) , and IDH2 mutations differed between astrocyti...
متن کاملPredicting 1p19q Chromosomal Deletion of Low-Grade Gliomas from MR Images using Deep Learning
Objective: Several studies have associated codeletion of chromosome arms 1p/19q in low-grade gliomas (LGG) with positive response to treatment and longer progression free survival. Therefore, predicting 1p/19q status is crucial for effective treatment planning of LGG. In this study, we predict the 1p/19q status from MR images using convolutional neural networks (CNN), which could be a noninvasi...
متن کاملErratum: Arm exercise stress testing: diagnostic options in stable coronary artery disease
[This corrects the article DOI: 10.1136/openhrt-2016-000461.].
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ژورنال
عنوان ژورنال: Neuro-Oncology Advances
سال: 2021
ISSN: 2632-2498
DOI: 10.1093/noajnl/vdab059